TOPO SURGICAL
Early development

Patient-specific surgical rehearsal, before the surgeon ever picks up an instrument.

We're developing a tool that lets surgeons rehearse an upcoming operation using the patient's own imaging — not a generic anatomical model, but the actual anatomy they'll be operating on.

Surgeons prepare for complex cases from flat imaging, and reconstruct the anatomy from memory.

CT and MRI scans are read as a stack of 2D slices. Turning that into a working 3D picture of a specific patient's vessel paths, tissue planes, and danger zones falls on the surgeon's own experience — before they've ever seen the anatomy in motion.

Structures that matter most aren't always easy to see or track from 2D imaging alone, and that gap shows up first in the OR, not before it.

Current workflow

Scan → radiologist read → mental 3D reconstruction → OR

No step in that chain lets a surgeon see, explore, or rehearse against the patient's actual anatomy before the day of surgery.

A patient's own scan, reconstructed into a 3D model a surgeon can review the day before.

We use computer vision and machine learning to process a patient's pre-operative CT or MRI and reconstruct it into a detailed, explorable 3D model — highlighting the structures that matter most for that specific case.

01 — Input

Pre-op scan

The patient's own CT or MRI, taken as part of standard pre-operative workup.

02 — Segment

Structure identification

Vessels, tissue planes, and the defect or target site are identified from the imaging.

03 — Reconstruct

3D model

Those structures are assembled into an explorable 3D reconstruction of that patient's anatomy.

04 — Review

Pre-op rehearsal

The surgeon reviews the model ahead of the case — same anatomy, same defect, before the OR.

Sarcoma

Danger zone highlighting

Tumor margins and surrounding vasculature — worked out before the incision.

Our first focus is sarcoma resection, developed in close collaboration with a practicing general surgeon whose clinical feedback has directly shaped the concept — including tumor margin visualization, proximity to vessels and nerves, and resection planning ahead of the operation.

The same case-specific model is also being explored as a training tool — giving surgical trainees a way to rehearse against real, patient-derived anatomy under supervision, not just idealized or generic cases.

Pre-prototype

This is early-stage. We're currently developing the core imaging pipeline and working toward a first proof of concept, guided directly by feedback from a practicing general surgeon.

Co-founders

Joseph Ikossi Le
Joseph Ikossi Le
Co-founder

Background in biochemistry and economics, with experience in biopharma and healthcare finance.

Alistair Joseph
Alistair Joseph
Co-founder

Background in computer engineering and economics, with experience as a software engineer at a FAANG company.

Danagra Ikossi, MD
Danagra Ikossi, MD, FACS
Stanford-trained robotic surgeon
  • Former Secretary, Treasurer, and Governor-at-Large, Northern California — Board of Directors, American College of Surgeons
  • Fellow, American College of Surgeons
  • Patients' Choice Award winner; Sutter Health MVP, #1 highest-performing physician in Northern and Central California

If you're a surgeon, researcher, or engineer interested in this problem, we'd like to hear from you.

joeikossile@gmail.com